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SR2

Tuscany and Lazio by motorhome

Pisa, wine country, cypress hills and a village on a crumbling rock. Ends in Rome, so plan for the ZTL.

Distance
349 km (217 mi)
Driving
4 h 49 min
Suggested days
5
Stops
8
Countries
Italy
Updated
September 20, 2026

At a glance: 5-day road trip of about 349 km (217 mi) with 8 stops, from Pisa to Rome. About 4 h 49 min of driving in total.

Route description

Start in Pisa at the Piazza dei Miracoli, where the leaning tower, cathedral and baptistery stand on a lawn; book tower climbs ahead in summer. Then head inland to Siena, whose shell-shaped Piazza del Campo hosts the Palio horse race each July and August.

South of Siena, follow the SR2 Via Cassia through the Crete Senesi to Montalcino, a hill town famous for Brunello wine. A farm stopover near Montalcino is a quiet place to spend the night among the vineyards, and there is also a farm campsite near San Quirico d’Orcia.

The Val d’Orcia around San Quirico is a UNESCO landscape of rolling hills lined with cypresses, and the best-known cypress group stands right beside the SR2. Continue south on the Via Cassia past Lake Bolsena to Civita di Bagnoregio, a hilltop village on crumbling clay, reached only by a steep footbridge; there is an entry fee.

The route ends in Rome. Most Italian historic centres, including Siena and Rome, are ZTL limited traffic zones monitored by cameras, and entering without a permit leads to fines, so stay at a campsite on the edge of Rome and use public transport into the city.

Stop-by-stop itinerary

In driving order. Distances are estimates between consecutive stops.

  1. 1

    Pisa

    Italy
    Start
  2. 2

    Piazza dei Miracoli

    HistoryPisa, Italy

    The leaning tower, cathedral and baptistery on a lawn. Book tower climbs ahead in summer.

    1 km
  3. 3

    Piazza del Campo

    HistorySiena, Italy

    A shell-shaped medieval square that hosts the Palio horse race each July and August.

    110 km
  4. 4

    Montalcino

    Italy
    40 km
  5. 5

    Farm campsite, San Quirico d'Orcia

    CampingSan Quirico d'Orcia, Italy
    11 km
  6. 6

    Val d'Orcia cypresses

    ViewsSan Quirico d’Orcia, Italy

    Rolling Tuscan hills lined with cypresses, a UNESCO landscape. The best-known cypress group is beside the SR2.

    1 km
  7. 7

    Civita di Bagnoregio

    OdditiesBagnoregio, Italy

    A hilltop village on crumbling clay, reached only by a steep footbridge. There is an entry fee.

    79 km
  8. 8

    Rome

    Italy
    108 km