Florida Gulf Coast and the Everglades
Shell beaches on Sanibel, Naples and the Tamiami Trail across the Everglades.
- Distance
- approx. 467 km (290 mi)
- Driving
- 5 h 11 min
- Suggested days
- 3
- Stops
- 6
- States
- FL
- Best time to go
- November–April
- Tolls and vignettes
- ≈ $7
- Updated
- July 19, 2026
At a glance: 3-day road trip of about 467 km (290 mi) with 6 stops, from Tampa to Miami. About 5 h 11 min of driving in total. Best time to go: November–April. Tolls and vignettes for a car: about $7 (FL).
More road trips in Florida
Photos along the route

Route description
From Tampa, follow I-75 or US-41 south along the Gulf Coast to Fort Myers, then take the causeway, where a toll is charged, to Sanibel. The island is known for shell beaches and the J. N. “Ding” Darling National Wildlife Refuge, where a one-way wildlife drive passes wading birds. The island is still recovering from Hurricane Ian in 2022.
Continue south to Naples, a neat resort town with a long pier and beaches on the Gulf. Just south, US-41 becomes the Tamiami Trail and runs east through Big Cypress National Preserve, a landscape of cypress swamps and prairies. A short detour on FL-29 leads to Everglades City, the gateway to the Ten Thousand Islands, with boat tours of the mangroves.
Farther east on the Tamiami Trail, Shark Valley has a 15-mile paved loop through sawgrass marsh, which you can cycle with a rented bike or ride on a tram tour. An observation tower at the halfway point offers wide views over the Everglades, and alligators often bask along the edges. The trail ends at Miami, where the city begins abruptly at the edge of the Everglades.
The dry season, from December to April, is the best time to visit, with more wildlife and fewer mosquitoes. Summer brings heat, afternoon thunderstorms and hurricanes. The Shark Valley parking lot fills early on winter weekends, so arrive in the morning.
Which stops are on Florida Gulf Coast and the Everglades?
In driving order. Distances are estimates between consecutive stops.
- 1Start
Tampa
FL - 2205 km
Sanibel
FL - 355 km
Naples
FL - 462 km
Everglades City
FL - 576 km
Shark Valley, Everglades
NatureMiami, FLA 15-mile paved loop through sawgrass, with alligators sunning at the edge. Rent a bike or take the tram.
- 669 km
Miami
FL
How do you drive Florida Gulf Coast and the Everglades in 3 days?
3 days, split by driving time. Campsites from OpenStreetMap: check opening dates before you go.
- Day 1: Tampa → Sanibel · 128 mi · 2 h 17 minOvernight nearby, for example: Red Coconut RV Resort (11 mi); Koreshan State Park Campground (18 mi).
- Day 2: Sanibel → Everglades City · 73 mi · 1 h 18 minOn the way: Naples.Overnight nearby, for example: Outdoor Resorts of Chokoloskee (3 mi); Monument Lake (17 mi).
- Day 3: Everglades City → Miami · 90 mi · 1 h 36 minOn the way: Shark Valley, Everglades.Overnight nearby, for example: Boca Chita Key Campground (17 mi); Larry and Penny Thompson Campground (17 mi).
When is the best time for Florida Gulf Coast and the Everglades?
The most pleasant months are usually November–April. Still fine, with some compromises, in May and September–October. Hot in June–August. July and August are the busiest months: book campsites early.
Estimate from long-term temperature averages, terrain and pass seasons
More routes for the best months
Practical guides for this route
Driving in the US: The Rules European Visitors Most Often Get Wrong at the Wheel
Fuel, Tolls and Distances: Practical US Driving Math for Motorhome and Camper Travelers
US national parks: entry fees, passes and reservations in plain terms
Themes
Plan this route for your vehicle
Scout adapts this route to your vehicle, your days and your budget.
FAQs
How long is Florida Gulf Coast and the Everglades?
3-day road trip of about 467 km (290 mi) with 6 stops, from Tampa to Miami. About 5 h 11 min of driving in total.
How many days do you need for Florida Gulf Coast and the Everglades?
We suggest 3 days: about 5 h 11 min of driving, which leaves time for the stops.
Where does Florida Gulf Coast and the Everglades start and end?
It starts in Tampa and ends in Miami.
Which states does Florida Gulf Coast and the Everglades pass through?
Florida.
Where can you camp along Florida Gulf Coast and the Everglades?
OpenStreetMap lists 74 campsites and motorhome stopovers within 19 mi of the stops on this route. For example: Encore Vacation Village, Outdoor Resorts of Chokoloskee and Red Coconut RV Resort.
How much are the tolls on Florida Gulf Coast and the Everglades?
Tolls and vignettes for a car: about $7 (FL). Estimate with typical rates; motorhomes pay more, and vehicles over 3.5 t often pay by distance.